Biff Seems to Be the Only One to Notice the Change

Then Biff watched as the man and woman acted as though everything were perfectly normal. Despite knowing he was male, the man was behaving in a feminine manner, while, also knowing that she was female, the woman was acting in a masculine manner. But Biff, Sarah, and that married couple were only the first to be changed. Like a wave, the changes continued, slowly expanding outward from Biff himself, until eventually, all of Lake Point would be affected.